Herpes simplex virus type 1 DNA polymerase. Mechanism-based affinity chromatography.
نویسندگان
چکیده
منابع مشابه
Anti-viral Effect and Mechanism of Carvacrol on Herpes Simplex Virus Type 1
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The processing of lagging-strand intermediates has not been demonstrated in vitro for herpes simplex virus type 1 (HSV-1). Human flap endonuclease-1 (Fen-1) was examined for its ability to produce ligatable products with model lagging-strand intermediates in the presence of the wild-type or exonuclease-deficient (exo(-)) HSV-1 DNA polymerase (pol). Primer/templates were composed of a minicircle...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1990
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(19)39085-4